During Week 4 of the 2021 season, Ashford and Straughn met in a regular season contest. The Ashford, AL program faced their counterparts from Andalusia, AL in this 2021 matchup. Straughn emerged victorious with a solid performance, defeating Ashford 33-20. The 13-point difference came in a game that saw 53 total points scored between the two teams. This Week 4 contest was one of many compelling matchups during the 2021 regular season.